diff --git a/nova/network/neutronv2/api.py b/nova/network/neutronv2/api.py
index 391ea8fb37bc..46bbfeebc621 100644
--- a/nova/network/neutronv2/api.py
+++ b/nova/network/neutronv2/api.py
@@ -1060,10 +1060,26 @@ class API(base_api.NetworkAPI):
         """Populate neutron binding:profile.
 
         Populate it with SR-IOV related information
+
+        :raises PciDeviceNotFound: If a claimed PCI device for the given
+            pci_request_id cannot be found on the instance.
         """
         if pci_request_id:
-            pci_dev = pci_manager.get_instance_pci_devs(
-                instance, pci_request_id).pop()
+            pci_devices = pci_manager.get_instance_pci_devs(
+                instance, pci_request_id)
+            if not pci_devices:
+                # The pci_request_id likely won't mean much except for tracing
+                # through the logs since it is generated per request.
+                LOG.error(
+                    _LE('Unable to find PCI device using PCI request ID in '
+                        'list of claimed instance PCI devices: %s. Is the '
+                        '[pci]/passthrough_whitelist configuration correct?'),
+                    # Convert to a primitive list to stringify it.
+                    list(instance.pci_devices), instance=instance)
+                raise exception.PciDeviceNotFound(
+                    _('PCI device not found for request ID %s.') %
+                    pci_request_id)
+            pci_dev = pci_devices.pop()
             profile = self._get_pci_device_profile(pci_dev)
             port_req_body['port'][BINDING_PROFILE] = profile
 
diff --git a/nova/tests/unit/network/test_neutronv2.py b/nova/tests/unit/network/test_neutronv2.py
index 0e6cc728ab7a..d9a77919b003 100644
--- a/nova/tests/unit/network/test_neutronv2.py
+++ b/nova/tests/unit/network/test_neutronv2.py
@@ -5059,6 +5059,19 @@ class TestNeutronv2Portbinding(TestNeutronv2Base):
             exception.PciDeviceNotFound, api._populate_neutron_binding_profile,
             instance, pci_req_id, port_req_body)
 
+    @mock.patch.object(pci_manager, 'get_instance_pci_devs', return_value=[])
+    def test_populate_neutron_binding_profile_pci_dev_not_found(
+            self, mock_get_instance_pci_devs):
+        api = neutronapi.API()
+        instance = objects.Instance(pci_devices=objects.PciDeviceList())
+        port_req_body = {'port': {}}
+        pci_req_id = 'my_req_id'
+        self.assertRaises(exception.PciDeviceNotFound,
+                          api._populate_neutron_binding_profile,
+                          instance, pci_req_id, port_req_body)
+        mock_get_instance_pci_devs.assert_called_once_with(
+            instance, pci_req_id)
+
     @mock.patch.object(pci_manager, 'get_instance_pci_devs')
     def test_pci_parse_whitelist_called_once(self,
                                              mock_get_instance_pci_devs):